Searchable abstracts of presentations at key conferences in endocrinology

ea0021p311 | Reproduction | SFEBES2009

A possible cardioprotective role for metformin in PCOS: a study of clot structure and fibrinolysis

Ajjan Ramzi A , Aggarwal Reena , Grant Peter J , Kilpatrick Eric S , Sathyapalan Thozhukat , Coady Anne-Marie , Atkin Stephen L

Introduction: Polycystic ovary syndrome (PCOS) is associated with known cardiovascular risk factors, consequently predisposing to premature cardiovascular disease. Blood clot structure has been shown to predict predisposition to atherothrombosis and the aim of this study was to investigate the effects of rimonabant and metformin on clot structure/function in women with PCOS.Methods: Twenty women with PCOS were recruited in a randomised open labelled para...